Colostrum (non-GMO)

Colostrum (non-GMO)

When mammals, including humans, are born the first food they receive is mother’s colostrum. This pre-milk fluid is a wonder of nature, packed with nourishment – immune tonics, growth factors and a unique balance of vitamins and minerals.

Colostrum supports healthy growth and development and a naturally responsive immune system. It provides critical immune factors and complex lipids for overall health and well-being.

For centuries the colostrum taken from animals has been consumed by children and adults. People in India have used it as a traditional remedy for thousands of years. Research over the past three decades has shown that bovine (cow) colostrum is one of the most effective nutritional supplements available for supporting many aspects of health, most notably:

  • A responsive immune system
  • Digestive tract integrity (preventing “leaky gut”)
  • Healthy aging
  • Natural healing and regeneration

Colostrum is a natural source of many bioactive compounds and valuable growth and immune factors that work synergistically to:

  • Improve your immune system and give greater health
  • Heal and protect the digestive tract
  • Enhance natural cellular repair, healing and tissue regeneration
  • Promote energy and vitality through healthy aging

Bovine colostrum is identical in molecular structure to the colostrum of humans but offers many more benefits. This is because bovine colostrum contains far greater nutrients and growth factors than human colostrum. For example, IgGs in bovine (cow) colostrum can be as high as 30% whereas human colostrum contains 2% IgG.

Bovine colostrum contains over ninety known compounds. Of these, primary components within bovine colostrum include:

  • immune factors (natural antibodies, immunoglobulins, prolin rich polypeptides, lactoferrin, cytokines, lymphokins, glycoproteins and leucocytes to name just a few)
  • growth factors that are vital to stimulate growth and help in the regeneration and acceleration of repair and renewal of muscle, skin, collagen, bone, cartilage and nerve tissue
  • vitamins, minerals and amino acids

Many human health benefits have been attributed to bovine colostrum including:

  • increased energy levels
  • strengthening of the immune system
  • association with lower risks of upper respiratory illnesses
  • anti-inflammatory and antioxidant responses
  • an increased ability to burn body fat and build lean muscle tissue
  • acceleration of healing after injury, illness and/or surgery
  • increased vitality, anti-aging and longevity properties
  • protection of the gut wall

General:

WebMD. (2005-2016). Bovine Colostrum. http://www.webmd.com/vitamins-supplements/ingredientmono-785-bovine%20colostrum.aspx?activeingredientid=785

Solomons, N. W. Modulation of the immune system and the response against pathogens with bovine colostrum concentrates. Eur.J.Clin.Nutr. 2002;56 Suppl 3:S24-S28. http://europepmc.org/abstract/med/12142957

Bagwe, S., Tharappel, L.J., Kaur, G., Buttar, H.S. (2015). Bovine colostrum: An emerging nutraceutical. Journal of Complementary & Integrative Medicine, 12(3): 175-185. doi: 10.1515/jcim-2014-0039. https://www.ncbi.nlm.nih.gov/pubmed/25781716 http://www.degruyter.com/view/j/jcim.2015.12.issue-3/jcim-2014-0039/jcim-2014-0039.xml (full article)

Kelly, G. S. Bovine colostrums: a review of clinical uses. Altern Med Rev 2003;8(4):378-394. http://go.galegroup.com/ps/anonymous?id=GALE%7CA111303981&sid=googleScholar&v=2.1&it=r&linkaccess=fulltext&issn=10895159&p=AONE&sw=w&authCount=1&isAnonymousEntry=true

Playford, R. J., MacDonald, C. E., Calnan, D. P., Floyd, D. N., Podas, T., Johnson, W., Wicks, A. C., Bashir, O., and Marchbank, T. Co-administration of the health food supplement, bovine colostrum, reduces the acute non-steroidal anti-inflammatory drug-induced increase in intestinal permeability. Clin.Sci.(Lond) 2001;100(6):627-633. http://www.colostrum4health.com/resources/Playford.pdf NOTE: This is a website in New Zealand that sells Colostrum products though I do not believe they are a real competitor.

Thapa, B. R. Health factors in colostrum. Indian J Pediatr 2005;72(7):579-581. http://www.cytolox.com/docs/Health%20Factors%20in%20Colostrum.pdf

Thapa, B. R. Therapeutic potentials of bovine colostrums. Indian J Pediatr 2005;72(10):849-852. http://medind.nic.in/icb/t05/i10/icbt05i10p849.pdf

Stelwagen K, Carpenter E, Haigh B, Hodgkinson A, Wheeler TT. Immune components of bovine colostrum and milk. Journal of Animal Science. 2009;2008;87:3-9. https://dl.sciencesocieties.org/publications/jas/abstracts/87/13_suppl/3

Playford RJ, Macdonald CE, Johnson WS. Colostrum and milk-derived peptide growth factors for the treatment of gastrointestinal disorders. Am J Clin Nutr 2000;72:5-14. http://www.holvita.co.uk/AJN.html

Godhia M.L, Patel N. Colostrum - its Composition, Benefits as a Nutraceutical - A Review. Curr Res Nutr Food Sci 2013;1(1):37-47. Available from: http://www.foodandnutritionjournal.org/?p=247

Cell Proliferation:

Klagsbrun, M. Bovine colostrum supports the serum-free proliferation of epithelial cells but not of fibroblasts in long-term culture. J.Cell Biol. 1980;84(3):808-814. http://jcb.rupress.org/content/84/3/808.full.pdf

Mero, A., Nykanen, T., Keinanen, O., Knuutinen, J., Lahti, K., Alen, M., Rasi, S., and Leppaluoto, J. Protein metabolism and strength performance after bovine colostrum supplementation. Amino.Acids 2005;28(3):327-335. http://link.springer.com/article/10.1007/s00726-005-0179-8

Skin:

Takayama, Y., Kitsunai, K., and Mizumachi, K. Factors in bovine colostrum that enhance the migration of human fibroblasts in type I collagen gels. Biosci.Biotechnol.Biochem. 2001;65(12):2776-2779. http://www.tandfonline.com/doi/pdf/10.1271/bbb.65.2776

Immune System:

Brinkworth, G. D. and Buckley, J. D. Concentrated bovine colostrum protein supplementation reduces the incidence of self-reported symptoms of upper respiratory tract infection in adult males. Eur.J.Nutr. 2003;42(4):228-232. http://www.tulipanesa.com/_documentos/file/ESTUDIO%20CURAMED.pdf

Davidson, G. P., Whyte, P. B., Daniels, E., Franklin, K., Nunan, H., McCloud, P. I., Moore, A. G., and Moore, D. J. Passive immunisation of children with bovine colostrum containing antibodies to human rotavirus. Lancet 9-23-1989;2(8665):709-712. http://www.sciencedirect.com/science/article/pii/S014067368990771X

Ebina, T., Ohta, M., Kanamaru, Y., Yamamoto-Osumi, Y., and Baba, K. Passive immunizations of suckling mice and infants with bovine colostrum containing antibodies to human rotavirus. J.Med.Virol. 1992;38(2):117-123. http://onlinelibrary.wiley.com/doi/10.1002/jmv.1890380209/full

Pacyna, J., Siwek, K., Terry, S. J., Roberton, E. S., Johnson, R. B., and Davidson, G. P. Survival of rotavirus antibody activity derived from bovine colostrum after passage through the human gastrointestinal tract. J.Pediatr.Gastroenterol.Nutr. 2001;32(2):162-167. http://journals.lww.com/jpgn/Abstract/2001/02000/Survival_of_Rotavirus_Antibody_Activity_Derived.13.aspx

Shield, J., Melville, C., Novelli, V., Anderson, G., Scheimberg, I., Gibb, D., and Milla, P. Bovine colostrum immunoglobulin concentrate for cryptosporidiosis in AIDS. Arch.Dis.Child 1993;69(4):451-453. http://adc.bmj.com/content/69/4/451.full.pdf

Heaton, P. Bovine colostrum immunoglobulin concentrate for cryptosporidiosis in AIDS. Arch.Dis.Child 1994;70(4):356-357. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1029802/pdf/archdisch00564-0100c.pdf

Saad K, Abo-Elela MGM, El-Baseer KAA, et al. Effects of bovine colostrum on recurrent respiratory tract infections and diarrhea in children. Medicine. 2016;95:e4560. http://journals.lww.com/md-journal/Fulltext/2016/09130/Effects_of_bovine_colostrum_on_recurrent.9.aspx

Greenberg PD, Cello JP. Treatment of severe diarrhea caused by Cryptosporidium parvum with oral bovine immunoglobulin concentrate in patients with AIDS. J Acquir Immune Defic Syndr Hum Retrovirol 1996;13:348-54. http://journals.lww.com/jaids/Fulltext/1996/12010/Treatment_of_Severe_Diarrhea_Caused_by.8.aspx

Huppertz HI, Rutkowski S, Busch DH, et al. Bovine colostrum ameliorates diarrhea in infection with diarrheogenic Escherichia coli, shiga toxin-producing E. Coli, and E. coli expressing intimin and hemolysin. J Pediatr Gastroenterol Nutr 1999;29:452-6. http://journals.lww.com/jpgn/Fulltext/1999/10000/Bovine_Colostrum_Ameliorates_Diarrhea_in_Infection.15.aspx

Mitra AK, Mahalanabis D, Ashraf H, et al. Hyperimmune cow colostrum reduces diarrhoea due to rotavirus: a double-blind, controlled clinical trial. Acta Paediatr 1995;84:996-1001. http://onlinelibrary.wiley.com/doi/10.1111/j.1651-2227.1995.tb13814.x/abstract

Nord J, Ma P, DiJohn D, et al. Treatment with bovine hyperimmune colostrum of cryptosporidial diarrhea in AIDS patients. AIDS 1990;4:581-4. http://journals.lww.com/aidsonline/Abstract/1990/06000/Treatment_with_bovine_hyperimmune_colostrum_of.15.aspx

Playford RJ, Floyd DN, Macdonald CE, et al. Bovine colostrum is a health food supplement which prevents NSAID induced gut damage. Gut 1999;44:653-8. http://gut.bmj.com/content/44/5/653.long

Rump JA, Arndt R, Arnold A, et al. Treatment of diarrhea in human immunodeficiency virus-infected patients with immunoglobulins from bovine colostrum. Clin Investig 1992;70:588-94. http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.688.4252&rep=rep1&type=pdf

Wong, E. B., Mallet, J., Duarte, J., Matar, C., Ritz, B. W. Bovine colostrum enhances natural killer cell activity and immune response in a mouse model of influenza infection and mediates intestinal immunity through toll-like receptors 2 and 4. Nutrition Research 2014; 34:318-325. https://www.researchgate.net/profile/Barry_Ritz/publication/261953387_Bovine_colostrum_enhances_natural_killer_cell_activity_and_immune_response_in_a_mouse_model_of_influenza_infection_and_mediates_intestinal_immunity_through_toll-like_receptors_2_and_4/links/5416e5700cf2fa878ad4339d.pdf

Cancer:

Sambasivarao, D., Hooton, J., Dost, A., and Paetkau, V. A novel immunosuppressive factor in bovine colostrum blocks activation of the interleukin 2 gene enhancer at the NFAT site. Biochem.Cell Biol. 1996;74(4):585-593. https://www.researchgate.net/profile/Axel_Dost/publication/14248075_A_novel_immunosuppressive_factor_in_bovine_colostrum_blocks_activation_of_the_interleukin_2_gene_enhancer_at_the_NFAT_site/links/04fd707917bdc6cc9fe42ae0.pdf

C. Stefani, C., Liverani, C.A. Bianco, V., Penna, C., et. al. Spontaneous regression of low-grade cervical intraepithelial lesions is positively improved by topical bovine colostrum preparations (GINEDIE®). A multicentre, observational, Italian pilot study. European Review for Medical and Pharmacological Sciences. 2014; 18: 728-733. https://www.researchgate.net/profile/Massimo_Origoni/publication/261105238_Spontaneous_regression_of_low-grade_cervical_intraepithelial_lesions_is_positively_improved_by_topical_bovine_colostrum_preparations_(GINEDIE)._A_multicentre_observational_italian_pilot_study/links/543fca010cf2be1758cfd4db.pdf

Hepatitis:

Sidhu S, Goyal O, Gupta A, Kishore H, Gupta A. Corticosteroids and Bovine Colostrum in Treatment of Alcoholic Hepatitis ‘In Extremis’: A Pilot Study. Journal of Clinical and Experimental Hepatology. 2015;5:S19-S20. http://www.jcehepatology.com/article/S0973-6883(15)00150-4/abstract

Multiple Sclerosis:

Ebina, T., Sato, A., Umezu, K., Aso, H., Ishida, N., Seki, H., Tsukamoto, T., Takase, S., Hoshi, S., and Ohta, M. Treatment of multiple sclerosis with anti-measles cow colostrum. Med Microbiol.Immunol 1984;173(2):87-93. http://link.springer.com/article/10.1007/BF02124822

Bayard, B. L. and James, M. A. Hyperimmune bovine colostrum inefficacious as multiple sclerosis therapy in double-blind study. J.Am.Diet.Assoc. 1987;87(10):1388-1390. http://agris.fao.org/agris-search/search.do?recordID=US19890042370

Anthrax:

Paddle, B. M., Wong, V. K., and Muller, B. D. The cytotoxic effect of anthrax lethal toxin on human lung cells in vitro and the protective action of bovine antibodies to PA and LF. J Appl Toxicol 2006;26(2):162-168. http://onlinelibrary.wiley.com/doi/10.1002/jat.1119/abstract

Colitis:

Khan Z, Macdonald C, Wicks AC, et al. Use of the 'nutriceutical', bovine colostrum, for the treatment of distal colitis: results from an initial study. Aliment Pharmacol Ther 2002;16:1917-22. http://onlinelibrary.wiley.com/doi/10.1046/j.1365-2036.2002.01354.x/full

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